Jing He | Biomimetic and Bio-inspired Composites | Best Researcher Award

Dr. Jing He | Biomimetic and Bio-inspired Composites | Best Researcher Award

Doctorate at Sichuan University, China

Profile:

🌟 Current Position

Jing He serves as an Associate Researcher at Sichuan University, where she is affiliated with the National Engineering Research Center for Biomaterials and the School of Biomedical Engineering. As a dedicated academic and doctoral supervisor, Jing He plays a pivotal role in advancing the field of biomaterials and tissue regeneration. Her current focus lies in developing innovative materials for the repair of bone, nerve, and skin tissues, ensuring impactful contributions to regenerative medicine.

📚 Publication Achievements

Jing He has established herself as a prolific researcher, with numerous publications in high-impact journals like Ceramics International and Rare Metals. These publications highlight her breakthroughs in tissue regeneration, particularly her research on:

  • Energy Metabolism Mechanisms: She demonstrated the connection between material-induced energy metabolism and AMPK-mTOR signaling, pivotal for spinal cord injury repair.
  • Mechanical Microenvironment Dynamics: Her work elucidates how mechanical stimuli regulate cellular behavior.

🔬 Ongoing Research

Bioenergetic Materials: Developing materials that optimize energy metabolism for enhanced tissue regeneration.

Hybrid Hydrogel Systems: Combining mechanical and biological cues to inhibit bone cancer recurrence while promoting regeneration.

Injectable Hydrogels: Designing collagen-based hydrogels for complex tissue repair applications.

These initiatives aim to bridge the gap between laboratory findings and clinical applications, revolutionizing regenerative medicine.

🌟 Research Interests

  • Tissue Regeneration: Exploring innovative strategies for repairing bone, nerve, and skin tissues.
  • Energy Metabolism and Biomaterials: Studying the AMPK-mTOR pathway and macrophage polarization to improve regenerative outcomes.
  • Mechanical Microenvironment: Investigating how mechanical stimuli influence cell behavior to design responsive biomaterials.
  • Cancer-Biomaterial Interactions: Developing materials to combat bone cancer and simultaneously promote healing.

🎓 Academic Background

Jing He earned her Ph.D. in biomedical engineering from a prestigious institution, specializing in material chemistry and tissue regeneration. Her doctoral research laid the foundation for her innovative work, integrating cutting-edge science with practical solutions for healthcare challenges.

🏆 Scholarships and Awards

Throughout her academic journey, Jing He has received numerous accolades, recognizing her excellence in research and dedication to advancing science. Her achievements reflect her commitment to addressing critical challenges in regenerative medicine and biomaterials.

💻 Bioinformatics Expertise

Jing He employs bioinformatics tools to analyze molecular pathways such as AMPK-mTOR and macrophage polarization. These insights are crucial for understanding cellular responses to biomaterials, enabling the design of highly effective regenerative therapies.

🌐 Professional Associations

Jing He is an active member of several professional associations related to biomaterials and biomedical engineering. Her involvement facilitates collaborations, keeping her at the forefront of emerging trends and innovations in her field.

🛠️ Training & Workshops

Jing He has participated in numerous training programs and workshops to enhance her technical expertise. These experiences include advanced scaffold fabrication, hydrogel synthesis, and molecular biology techniques, equipping her with skills essential for groundbreaking research.

🗣️ Oral Presentations

Jing He has delivered impactful oral presentations at international conferences, sharing her research on:

  • The role of energy metabolism in tissue regeneration.
  • Innovations in hybrid hydrogel systems.
    Her presentations have inspired academic and industrial stakeholders, promoting the practical application of her findings.

✅ Tasks Completed as a Researcher

  • Designing collagen-based injectable hydrogels for complex tissue regeneration.
  • Establishing mechanisms linking energy metabolism and axonal repair.
  • Developing hybrid hydrogel technologies for cancer inhibition and bone repair.
    These accomplishments underscore her ability to translate theoretical knowledge into tangible innovations.

🌟 Success Factors

Jing He’s success stems from her interdisciplinary expertise, creativity, and dedication. Her ability to merge material science, biology, and engineering has led to solutions that address pressing medical challenges, cementing her legacy as a transformative researcher.

🌟 A Visionary in Regenerative Medicine

Jing He’s contributions to science are profound, blending innovation with practical solutions for healthcare. Her work not only addresses critical challenges in tissue engineering but also inspires the next generation of researchers to strive for excellence.

📖Publications:

Paper Title: Reinforced enzyme mineralized chitosan hydrogels with superior mechanical and osteogenic properties

  • Authors: Wang, Y., Zhang, N., Zhang, J., He, J., Wu, F.
  • Journal: Carbohydrate Polymers
  • Year: 2025

Paper Title: Construction of ROS-balancing-engineered heterojunction photoswitch for achieving programmed inflammatory management and tissue regeneration

  • Authors: Luo, B., He, J., Lei, J., Lan, F., Wu, Y.
  • Journal: Chemical Engineering Journal
  • Year: 2024

Paper Title: Succinic acid modified chitosan hydrogel mediates in-situ bioenergetic remodeling of neural cells for neuronal differentiation and spinal cord injury repair

  • Authors: Xu, T., Zhao, J., Zhou, M., Wu, F., He, J.
  • Journal: Chemical Engineering Journal
  • Year: 2024

Paper Title: Fructose-mineralized black phosphorus for syncretic bone regeneration and tumor suppression

  • Authors: Shu, J., Wang, Y., Zhang, G., Wu, F., He, J.
  • Journal: Journal of Materials Chemistry B
  • Year: 2024

Paper Title: Inorganic Phosphate as “Bioenergetic Messenger” Triggers M2-Type Macrophage Polarization

  • Authors: Sun, X., Li, Z., Wang, X., He, J., Wu, Y.
  • Journal: Advanced Science
  • Year: 2024

 

Rui Wen | Natural Fibers | Best Researcher Award

Assist Prof Dr. Rui Wen | Natural Fibers | Best Researcher Award

Wenzhou Medical University, China

Profiles:

Current Position 🌟

Rui Wen is currently an Assistant Professor at Wenzhou Medical University, where he is actively engaged in cutting-edge research on biomaterials. He focuses primarily on studying the functional properties of silk proteins and the synthesis of artificial spider silk fibers with advanced mechanical attributes. His work bridges the fields of biomaterials and bioengineering, positioning him as a promising figure in materials science and biotechnology.

Publication Achievements 📚

With a strong foundation in biomaterials research, Rui Wen has contributed significantly to the field through numerous high-impact publications. As the first author or corresponding author, he has published 11 peer-reviewed papers in prestigious journals, including the International Journal of Biological Macromolecules, Acta Biomaterialia, and ACS Biomaterials Science & Engineering. His publications address the functional aspects of spider silk proteins and the synthesis of artificial silk fibers, advancing both the scientific understanding and application potential of silk-based materials.

Ongoing Research and Innovations 🔬

Rui Wen’s research currently focuses on two main aspects of spider silk. First, he conducts in-depth analyses of spider silk protein compositions, aiming to uncover the natural mechanisms that give spider silk its remarkable mechanical properties. This understanding forms the basis for synthetic replication in lab settings. Second, he explores artificial spider silk production, concentrating on enhancing the extensibility and strength of the fibers. His recent work demonstrated that by adjusting the molecular weight of spider silk proteins, it is possible to create synthetic fibers with properties exceeding those of natural spider silk. This advancement lays the groundwork for future applications in high-performance materials.

Research Interests 🧬

Rui Wen’s research interests span the biomimetic study of spider silk proteins, the molecular synthesis of silk-based materials, and bioengineering applications for high-strength fibers. His work explores both the natural composition of spider silk proteins and their synthetic adaptation to improve properties like tensile strength, elasticity, and durability. This interdisciplinary focus positions his research at the intersection of biotechnology, materials science, and engineering.

Academic Background 🎓

Rui Wen received his Ph.D. in Biomaterials from Donghua University in 2020. His academic journey has been shaped by an interest in biomimicry and the pursuit of sustainable, high-performance materials. His foundational studies laid the groundwork for his subsequent research on artificial spider silk, a field where he continues to push boundaries.

Collaborations and Professional Network 🤝

Collaboration is central to Rui Wen’s research. In partnership with Professor Xiangqin Liu at Dalhousie University, he made a breakthrough in spider silk research, co-authoring a paper that introduced the first full-length coding gene for wrapped silk protein in China. This finding, published in International Journal of Biological Macromolecules in 2018, represents a critical contribution to the genetic understanding of spider silk and has furthered his professional reputation. He also maintains professional connections with colleagues Xue Li, Kangkang Wang, Suyang Wang, and Qing Meng, contributing to a network that fosters innovation in biomaterials.

Editorial Appointments and Review Responsibilities 📝

Rui Wen’s editorial and review roles reflect his expertise in biomaterials. He serves on the editorial board of the World Journal of Biological Chemistry and the Young Editorial Board for Biomedical Engineering Communications. Additionally, he acts as an invited reviewer for the International Journal of Biological Macromolecules. These positions allow him to shape the discourse in biomaterials and bioengineering while staying updated on the latest scientific advancements.

Professional Associations and Memberships 🏛️

Rui Wen is actively engaged with the scientific community through his memberships in professional associations alongside prominent researchers such as Xue Li and Kangkang Wang. These affiliations support his commitment to collaborative research and knowledge sharing within the biomaterials field.

Training, Workshops, and Oral Presentations 🎤

Throughout his career, Rui Wen has participated in workshops and conferences focused on materials science, biomimetics, and spider silk research. His presentations have contributed to the broader understanding of silk protein synthesis and fiber properties. These opportunities have enabled him to refine his expertise, exchange ideas with other experts, and enhance the visibility of his work.

Key Contributions to Biomimetic Research 🌍

Rui Wen’s contributions to biomimetic research are centered on unraveling the complexities of spider silk proteins. By systematically studying the molecular composition of spider wrapping silk fibers, he has identified key proteins that contribute to the material’s exceptional properties. His insights into the protein composition and molecular weight relationships have been instrumental in developing high-performance synthetic fibers that may one day be applied in various fields, from medicine to aerospace.

Success Factors and Research Milestones 🏆

Rui Wen attributes his success to a disciplined approach to research, continuous learning, and collaborative engagement. His landmark achievements, including the genetic analysis of spider silk proteins and the development of artificial silk fibers with improved extensibility, mark important milestones in the field of biomaterials. His work has garnered attention for its potential to revolutionize sustainable material synthesis.

Publications and Laboratory Experience 🧪

With over 16 publications in SCI-indexed and Scopus journals, Rui Wen’s scholarly output reflects a high level of scientific rigor. His laboratory experience encompasses advanced techniques in protein characterization, gene sequencing, and fiber synthesis. In the lab, he works with state-of-the-art equipment to explore the biomimetic applications of silk proteins and innovate synthetic fiber production.

Sustainable Silk-Based Materials 🌱

Looking ahead, Rui Wen envisions a future where artificial spider silk fibers play a role in sustainable development. His ongoing research on silk protein functions and fiber synthesis holds promise for reducing the environmental impact of synthetic materials. Through continuous innovation, he aims to create sustainable materials that meet the demands of modern industries while preserving natural resources.

📖Publications:

Paper Title: Physical Properties of the Second Type of Aciniform Spidroin (AcSp2) from Neoscona theisi Reveal a pH-Dependent Self-Assembly Repetitive Domain

  • Authors: Yang, D., Wang, S., Wang, K., Zan, X., Wen, R.
  • Journal: ACS Biomaterials Science and Engineering
  • Year: 2023

Paper Title: Complete gene sequence and mechanical property of the fourth type of major ampullate silk protein

  • Authors: Wen, R., Wang, S., Wang, K., Zan, X., Meng, Q.
  • Journal: Acta Biomaterialia
  • Year: 2023

Paper Title: Characterization of two full-length tubuliform silk gene sequences from Neoscona theisi reveals intragenic concerted evolution and multiple copies in genome

  • Authors: Wen, R., Wang, K., Zan, X.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2022

Paper Title: Characterization of two full-length Araneus ventricosus major ampullate silk protein genes

  • Authors: Wen, R., Yang, D., Wang, K., Zan, X.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2022

Paper Title: The novel aciniform silk protein (AcSp2-v2) reveals the unique repetitive domain with high acid and thermal stability and self-assembly capability

  • Authors:Wen, R., Wang, K., Yang, D., Zan, X., Meng, Q.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2022

 

Yufeng Xing | Composite Materials Science | Best Researcher Award

Prof Dr. Yufeng Xing | Composite Materials Science | Best Researcher Award

Professor at Shenzhen Traditional Chinese Medicine Hospital, China

Profile:

Current Position🏥

Professor Yufeng Xing, M.D., is a prominent figure in the field of liver disease research, holding several key roles in prestigious medical institutions. He serves as the Director of the Department of Liver Disease at the Shenzhen Traditional Chinese Medicine (TCM) Hospital. Additionally, he leads the National Key Specialized and Key Discipline Research Office of Hepatology of TCM. His influence extends further as the Deputy Director of the South China Center for TCM Liver Disease Diagnosis and Treatment under the State Administration of TCM. His academic affiliations include his role as the head of the Institute of Liver Disease at the Fourth Clinical College of Guangzhou University of TCM.

In recognition of his expertise, Professor Xing has been named a Guangdong Outstanding Young Medical Talent, a Shenzhen Chinese Medicine Leading Talent, and a Shenzhen High-Level Talent. Moreover, he is part of the Shenzhen Health Committee Elite Talent Program as a subject leader for training, showcasing his growing influence in medical education and research.

Publication Achievements📚

Professor Xing has an extensive body of work, with over 40 academic papers published, including 15 SCI-indexed papers. His research has made a significant impact in the field of liver diseases, particularly with his studies focusing on viral hepatitis, metabolic-associated fatty liver disease (MAFLD), cirrhosis, and liver cancer. His collaborative and individual contributions have resulted in eight national and provincial science and technology achievement awards and the authorship of three monographs. These publications have garnered recognition from both domestic and international communities, further solidifying his reputation as a leading expert in liver disease and TCM.

Ongoing Research🔬

Professor Xing’s ongoing research is centered on leveraging Traditional Chinese Medicine in the fight against liver diseases. His work spans several critical areas:

  • Viral hepatitis, MAFLD, cirrhosis, and liver cancer: His research focuses on understanding and treating these conditions through innovative TCM approaches.
  • Application of network pharmacology and bioinformatics: He utilizes cutting-edge techniques such as network pharmacology and bioinformatics to explore the prevention and treatment of liver diseases with TCM, aiming to improve therapeutic outcomes.
  • Biomaterials and nanocarriers: His work also delves into the innovation, research, and development of biomaterials and nanocarriers for targeted treatment of liver diseases, representing a promising future direction in both Western and Chinese medicine.

Research Interests🔍

Professor Xing’s primary research interests lie in the intersection of Traditional Chinese Medicine and modern biomedical technology. His expertise in liver diseases, particularly viral hepatitis and liver cancer, highlights his commitment to integrating ancient medical knowledge with modern scientific discoveries. Moreover, his focus on the application of network pharmacology and bioinformatics in liver disease prevention through TCM opens new possibilities in personalized medicine. His research in biomaterials and nanocarriers further showcases his innovative mindset, blending material science and medical science for breakthrough treatments.

Academic Background🎓

Professor Xing’s distinguished career is underpinned by a strong academic foundation. His journey through the fields of medicine and traditional Chinese medicine has been marked by continual learning and research excellence. As a doctoral supervisor and postdoctoral cosupervisor, he plays an active role in shaping the next generation of scholars and medical professionals, further advancing TCM as a modern and respected discipline.

Scholarships and Awards🏆

Throughout his career, Professor Xing has earned numerous accolades, affirming his contributions to medical science and education. Among his most notable recognitions are his awards from provincial and national bodies for his scientific achievements. His leadership roles in prestigious medical and research institutions are a testament to his contributions, with awards like the Shenzhen Chinese Medicine Leading Talent highlighting his influence in the field.

Bioinformatics💻

Professor Xing has integrated bioinformatics into his research on liver diseases, particularly within the context of Traditional Chinese Medicine. Through network pharmacology approaches, he identifies key molecular mechanisms and potential therapeutic targets for liver disease. This innovative use of bioinformatics has enabled Professor Xing to predict the interactions between herbal compounds and biological systems, opening up new possibilities for the prevention and treatment of complex liver diseases.

Professional Associations🌐

Professor Xing is actively involved in various professional organizations. He serves as the Vice President and Secretary General of the East China Southern TCM Liver Disease Alliance, and as Deputy Secretary General of the Hepatology Branch of the Chinese Society of Ethnic Medicine. He is also a standing member of several other important bodies, including the Hepatobiliary Diseases Branch of the Chinese Association of Traditional Chinese Medicine and the Executive Director of the Infectious Diseases Branch of the Chinese Society of Ethnic Medicine. His involvement in these organizations reflects his leadership in promoting liver disease research and treatment, particularly through the lens of Traditional Chinese Medicine.

Training & Workshops🏅

In his dedication to knowledge dissemination, Professor Xing actively participates in and conducts training programs and workshops. These events focus on advancements in liver disease treatments and Traditional Chinese Medicine. His mentorship extends to both aspiring researchers and established professionals, bridging the gap between ancient practices and cutting-edge scientific research.

Oral Presentations🎤

Professor Xing is a sought-after speaker at national and international conferences, where he shares his expertise on liver diseases and the integration of Traditional Chinese Medicine with modern bioinformatics. His presentations are well-received by the scientific community, as they often provide insights into innovative treatments and the application of TCM in complex diseases.

Tasks Completed as a Researcher🔑

Throughout his career, Professor Xing has played a pivotal role in over 20 major research projects at the national, provincial, and municipal levels, including the 11th, 12th, and 13th Five-Year Plan initiatives. His contributions to these projects have led to advancements in both the understanding and treatment of liver diseases, particularly through the integration of TCM with modern medical techniques.

Success Factors🏆

Professor Xing’s success can be attributed to his dedication to interdisciplinary research, combining Traditional Chinese Medicine with modern bioinformatics and material sciences. His ability to innovate, mentor young researchers, and continuously advance the field of liver disease treatments sets him apart as a leading figure in medical research.

Publications & Laboratory Experience🧪

With a focus on clinical and laboratory-based research, Professor Xing’s contributions have significantly advanced the understanding of liver diseases. His work in bioinformatics, nanocarriers, and network pharmacology offers new insights into how liver diseases can be treated using TCM-based methodologies, particularly at the molecular level. His publications serve as critical resources for future researchers in these fields.

📖Publications:

Paper Title: ROS-responsive injectable hydrogels loaded with exosomes carrying miR-4500 reverse liver fibrosis

  • Authors: Yang, H., Wang, W., Xiao, J., Xu, L., Xing, Y.
  • Journal: Biomaterials
  • Year: 2025

Paper Title: Competitive adsorption of microRNA-532-3p by circular RNA SOD2 activates Thioredoxin Interacting Protein/NLR family pyrin domain containing 3 pathway and promotes pyroptosis of non-alcoholic fatty hepatocytes

  • Authors: Chen, F., Xing, Y., Chen, Z., Luo, F., Cai, Q.
  • Journal: European Journal of Medical Research
  • Year: 2024

Paper Title: Woman with epigastric pain after massage

  • Authors: Zhong, Z., Xing, Y., Wu, Y., Guo, S.
  • Journal: JACEP Open
  • Year: 2024

Paper Title: From gut to liver: unveiling the differences of intestinal microbiota in NAFL and NASH patients

  • Authors: Huang, F., Lyu, B., Xie, F., Tong, G., Fengping, X.
  • Journal: Frontiers in Microbiology
  • Year: 2024

Paper Title: A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment

  • Authors: Chen, M., Huang, F., Chen, B., Zhou, H., Tong, G.
  • Journal: Biomedicine and Pharmacotherapy
  • Year: 2023