Jing He | Biomimetic and Bio-inspired Composites | Best Researcher Award

Dr. Jing He | Biomimetic and Bio-inspired Composites | Best Researcher Award

Doctorate at Sichuan University, China

Profile:

๐ŸŒŸ Current Position

Jing He serves as an Associate Researcher at Sichuan University, where she is affiliated with the National Engineering Research Center for Biomaterials and the School of Biomedical Engineering. As a dedicated academic and doctoral supervisor, Jing He plays a pivotal role in advancing the field of biomaterials and tissue regeneration. Her current focus lies in developing innovative materials for the repair of bone, nerve, and skin tissues, ensuring impactful contributions to regenerative medicine.

๐Ÿ“š Publication Achievements

Jing He has established herself as a prolific researcher, with numerous publications in high-impact journals like Ceramics International and Rare Metals. These publications highlight her breakthroughs in tissue regeneration, particularly her research on:

  • Energy Metabolism Mechanisms: She demonstrated the connection between material-induced energy metabolism and AMPK-mTOR signaling, pivotal for spinal cord injury repair.
  • Mechanical Microenvironment Dynamics: Her work elucidates how mechanical stimuli regulate cellular behavior.

๐Ÿ”ฌ Ongoing Research

Bioenergetic Materials: Developing materials that optimize energy metabolism for enhanced tissue regeneration.

Hybrid Hydrogel Systems: Combining mechanical and biological cues to inhibit bone cancer recurrence while promoting regeneration.

Injectable Hydrogels: Designing collagen-based hydrogels for complex tissue repair applications.

These initiatives aim to bridge the gap between laboratory findings and clinical applications, revolutionizing regenerative medicine.

๐ŸŒŸ Research Interests

  • Tissue Regeneration: Exploring innovative strategies for repairing bone, nerve, and skin tissues.
  • Energy Metabolism and Biomaterials: Studying the AMPK-mTOR pathway and macrophage polarization to improve regenerative outcomes.
  • Mechanical Microenvironment: Investigating how mechanical stimuli influence cell behavior to design responsive biomaterials.
  • Cancer-Biomaterial Interactions: Developing materials to combat bone cancer and simultaneously promote healing.

๐ŸŽ“ Academic Background

Jing He earned her Ph.D. in biomedical engineering from a prestigious institution, specializing in material chemistry and tissue regeneration. Her doctoral research laid the foundation for her innovative work, integrating cutting-edge science with practical solutions for healthcare challenges.

๐Ÿ† Scholarships and Awards

Throughout her academic journey, Jing He has received numerous accolades, recognizing her excellence in research and dedication to advancing science. Her achievements reflect her commitment to addressing critical challenges in regenerative medicine and biomaterials.

๐Ÿ’ป Bioinformatics Expertise

Jing He employs bioinformatics tools to analyze molecular pathways such as AMPK-mTOR and macrophage polarization. These insights are crucial for understanding cellular responses to biomaterials, enabling the design of highly effective regenerative therapies.

๐ŸŒ Professional Associations

Jing He is an active member of several professional associations related to biomaterials and biomedical engineering. Her involvement facilitates collaborations, keeping her at the forefront of emerging trends and innovations in her field.

๐Ÿ› ๏ธ Training & Workshops

Jing He has participated in numerous training programs and workshops to enhance her technical expertise. These experiences include advanced scaffold fabrication, hydrogel synthesis, and molecular biology techniques, equipping her with skills essential for groundbreaking research.

๐Ÿ—ฃ๏ธ Oral Presentations

Jing He has delivered impactful oral presentations at international conferences, sharing her research on:

  • The role of energy metabolism in tissue regeneration.
  • Innovations in hybrid hydrogel systems.
    Her presentations have inspired academic and industrial stakeholders, promoting the practical application of her findings.

โœ… Tasks Completed as a Researcher

  • Designing collagen-based injectable hydrogels for complex tissue regeneration.
  • Establishing mechanisms linking energy metabolism and axonal repair.
  • Developing hybrid hydrogel technologies for cancer inhibition and bone repair.
    These accomplishments underscore her ability to translate theoretical knowledge into tangible innovations.

๐ŸŒŸ Success Factors

Jing Heโ€™s success stems from her interdisciplinary expertise, creativity, and dedication. Her ability to merge material science, biology, and engineering has led to solutions that address pressing medical challenges, cementing her legacy as a transformative researcher.

๐ŸŒŸ A Visionary in Regenerative Medicine

Jing Heโ€™s contributions to science are profound, blending innovation with practical solutions for healthcare. Her work not only addresses critical challenges in tissue engineering but also inspires the next generation of researchers to strive for excellence.

๐Ÿ“–Publications:

Paper Title: Reinforced enzyme mineralized chitosan hydrogels with superior mechanical and osteogenic properties

  • Authors: Wang, Y., Zhang, N., Zhang, J., He, J., Wu, F.
  • Journal: Carbohydrate Polymers
  • Year: 2025

Paper Title: Construction of ROS-balancing-engineered heterojunction photoswitch for achieving programmed inflammatory management and tissue regeneration

  • Authors: Luo, B., He, J., Lei, J., Lan, F., Wu, Y.
  • Journal: Chemical Engineering Journal
  • Year: 2024

Paper Title: Succinic acid modified chitosan hydrogel mediates in-situ bioenergetic remodeling of neural cells for neuronal differentiation and spinal cord injury repair

  • Authors: Xu, T., Zhao, J., Zhou, M., Wu, F., He, J.
  • Journal: Chemical Engineering Journal
  • Year: 2024

Paper Title: Fructose-mineralized black phosphorus for syncretic bone regeneration and tumor suppression

  • Authors: Shu, J., Wang, Y., Zhang, G., Wu, F., He, J.
  • Journal: Journal of Materials Chemistry B
  • Year: 2024

Paper Title: Inorganic Phosphate as โ€œBioenergetic Messengerโ€ Triggers M2-Type Macrophage Polarization

  • Authors: Sun, X., Li, Z., Wang, X., He, J., Wu, Y.
  • Journal: Advanced Science
  • Year: 2024

 

Fangyin Dai | Natural Fibers | Best Innovation Award

Prof Dr. Fangyin Dai | Natural Fibers | Best Innovation Award

Southwest University, China

Profiles:

Current Position๐Ÿ“˜

Professor Fangyin Dai is a distinguished researcher and professor at Southwest University in Chongqing, China. Renowned for his profound contributions to the fields of silkworm genetics, biomaterials, and gene functional studies, Prof. Dai’s work has laid the groundwork for advancements in biotechnological applications. His academic journey has been marked by a focus on understanding silkworm resources, exploring genetic mapping, and the functional characterization of mutant genes. This focus on biomaterials is an extension of his expertise in silkworm genetics, making him a leading figure in both genetics and innovative material sciences.

Publication Achievements and Recognition ๐Ÿ“š

Prof. Daiโ€™s publishing record is prolific, with over 400 research papers in top-tier journals, including Science, Nature Biotechnology, and Nature Communications. His contributions have garnered a citation index of 5627, an H-index of 27, and a G-index of 73, reflecting his extensive impact on the fields of biology, genetics, and biomaterials. His research has opened new pathways in functional genomics, enabling other researchers to explore and build upon his findings, especially in silkworm biology.

Research Projects and Innovations ๐Ÿ”ฌ

Throughout his career, Prof. Dai has spearheaded more than 30 research projects, many under Chinaโ€™s prestigious National 863 Program and the National Natural Science Foundation. Notably, he developed the world’s largest gene bank for silkworms. His genetic studies have led to groundbreaking discoveries of 35 new mutant types of silkworms, each providing unique insights into traits associated with color, body shape, and development. His commitment to innovation in biomaterials has also led to the development of five new silkworm varieties, pushing the boundaries of functional and structural biology.

Ongoing Research: Genetic Mutations and Biomaterial Applications ๐Ÿงฌ

Prof. Daiโ€™s current work emphasizes the genetic mapping and cloning of silkworm traits, with an interest in the molecular basis of specific mutations. His labโ€™s ongoing research focuses on identifying the molecular mechanisms that drive physical and behavioral traits in silkworms, revealing insights that benefit not only genetics but also the development of silk-based biomaterials. As a result, his research contributes directly to fields such as textile engineering and medical biomaterials.

Contributions to Silkworm Breeding and Genetic Resources ๐ŸŒฑ

A notable achievement of Prof. Dai is his work in creating breeding materials and new silkworm varieties. By carefully studying and documenting the inheritance and linkage of silkworm traits, he developed methods to engineer traits like pigmentation and resilience. His successful deciphering of critical silkworm genes has made it possible to produce biomaterials tailored for specific functions, whether for stronger textiles or biodegradable materials in medicine. His expertise has made significant strides in sustainable biomaterials by harnessing natural resources.

Scholarships and Awards ๐Ÿฅ‡

Prof. Dai has received several prestigious awards for his pioneering work, though details of specific honors were not provided. His achievements have been recognized by leading institutions and societies focused on biomaterials, genetics, and applied biology.

Professional Associations and Editorial Roles ๐Ÿ…

As a respected figure in biomaterial research and genetics, Prof. Dai is a member of several professional organizations related to biology and biomaterials. His work has led him to collaborate with other prominent researchers worldwide, especially in projects focused on genetic modification and application of silk-based materials in medical fields. He also serves as an editorial member of leading scientific journals, offering his expertise in genetics and biomaterials to guide the future of academic publications.

Training & Workshops and Bioinformatics Contributions ๐Ÿ’ป

Prof. Dai has been active in training upcoming scientists in genetics and biomaterials. Through workshops and academic programs, he introduces students and researchers to cutting-edge techniques in bioinformatics and silkworm gene mapping. His bioinformatics expertise enables him to analyze complex genetic information, accelerating discoveries and improving understanding of biomaterial applications.

Oral Presentations and Conferences ๐ŸŽค

Known for his engaging presentations, Prof. Dai regularly participates in international conferences where he shares his findings on genetic mutations in silkworms and their implications for biomaterials. His talks focus on the applied genetics of silkworms, covering both the scientific details of his research and its practical applications in the materials sciences.

Success Factors and Publications ๐Ÿ“œ

Prof. Daiโ€™s success stems from his commitment to scientific excellence and innovation. His work is rooted in collaborative research, as seen in his project with international colleagues to map silkworm genes. His dedication to expanding the applications of his findings is also evident in his numerous publications, where he details breakthroughs in silk-based biomaterials and genetically engineered silkworms. The comprehensive resources he has developed are invaluable for further research, and his numerous publications document these achievements, serving as critical references for other researchers in the field.

Key Projects and Laboratory Experience ๐Ÿ”

In addition to his genetic research, Prof. Dai’s laboratory is equipped with state-of-the-art technology for the study of silkworm biomaterials. He has led projects that investigate the structural and functional aspects of these materials, with applications that extend from biomedicine to sustainable textiles. His teamโ€™s laboratory work, which focuses on replicating natural materials, is at the forefront of biomaterial research.

Vision and Future Prospects ๐ŸŒŽ

With a commitment to pushing the boundaries of genetics and biomaterials, Prof. Dai continues to influence these fields profoundly. His work in silkworm biomaterials and genetic mapping contributes to both the understanding of biological processes and the development of sustainable technologies. His legacy is one of innovation, bridging genetics with practical applications and paving the way for the next generation of biomaterials.

๐Ÿ“–Publications:

Paper Title: PupaNet: A versatile and efficient silkworm pupae (Bombyx mori) identification tool for sericulture breeding based on near-infrared spectroscopy and deep transfer learning

  • Authors: He, H., Huang, H., Zhu, S., Dai, F., Zhao, T.
  • Journal: Computers and Electronics in Agriculture
  • Year: 2024

Paper Title: Cuproptosis-based layer-by-layer silk fibroin nanoplatform-loaded PD-L1 siRNA combining photothermal and chemodynamic therapy against metastatic breast cancer

  • Authors: Li, Z., Cheng, L., Xu, X., Xiao, B., Dai, F.
  • Journal: Materials Today Bio
  • Year: 2024

Paper Title: QTL analysis to identify genes involved in the trade-off between silk protein synthesis and larva-pupa transition in silkworms

  • Authors: Gao, R., Li, C., Zhou, A., Tong, X., Dai, F.
  • Journal: Genetics Selection Evolution
  • Year: 2024

Paper Title: FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species

  • Authors: Song, J., Li, Z., Zhou, L., Rasmussen, L.J., Dai, F.
  • Journal: Nature Communications
  • Year: 2024

Paper Title: Flat silk cocoons: A candidate material for fabricating lightweight and impact-resistant composites

  • Authors: Shao, J., Liu, Y., Hou, Z., Dai, F., Cheng, L.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2024

 

Rui Wen | Natural Fibers | Best Researcher Award

Assist Prof Dr. Rui Wen | Natural Fibers | Best Researcher Award

Wenzhou Medical University, China

Profiles:

Current Position ๐ŸŒŸ

Rui Wen is currently an Assistant Professor at Wenzhou Medical University, where he is actively engaged in cutting-edge research on biomaterials. He focuses primarily on studying the functional properties of silk proteins and the synthesis of artificial spider silk fibers with advanced mechanical attributes. His work bridges the fields of biomaterials and bioengineering, positioning him as a promising figure in materials science and biotechnology.

Publication Achievements ๐Ÿ“š

With a strong foundation in biomaterials research, Rui Wen has contributed significantly to the field through numerous high-impact publications. As the first author or corresponding author, he has published 11 peer-reviewed papers in prestigious journals, including the International Journal of Biological Macromolecules, Acta Biomaterialia, and ACS Biomaterials Science & Engineering. His publications address the functional aspects of spider silk proteins and the synthesis of artificial silk fibers, advancing both the scientific understanding and application potential of silk-based materials.

Ongoing Research and Innovations ๐Ÿ”ฌ

Rui Wenโ€™s research currently focuses on two main aspects of spider silk. First, he conducts in-depth analyses of spider silk protein compositions, aiming to uncover the natural mechanisms that give spider silk its remarkable mechanical properties. This understanding forms the basis for synthetic replication in lab settings. Second, he explores artificial spider silk production, concentrating on enhancing the extensibility and strength of the fibers. His recent work demonstrated that by adjusting the molecular weight of spider silk proteins, it is possible to create synthetic fibers with properties exceeding those of natural spider silk. This advancement lays the groundwork for future applications in high-performance materials.

Research Interests ๐Ÿงฌ

Rui Wenโ€™s research interests span the biomimetic study of spider silk proteins, the molecular synthesis of silk-based materials, and bioengineering applications for high-strength fibers. His work explores both the natural composition of spider silk proteins and their synthetic adaptation to improve properties like tensile strength, elasticity, and durability. This interdisciplinary focus positions his research at the intersection of biotechnology, materials science, and engineering.

Academic Background ๐ŸŽ“

Rui Wen received his Ph.D. in Biomaterials from Donghua University in 2020. His academic journey has been shaped by an interest in biomimicry and the pursuit of sustainable, high-performance materials. His foundational studies laid the groundwork for his subsequent research on artificial spider silk, a field where he continues to push boundaries.

Collaborations and Professional Network ๐Ÿค

Collaboration is central to Rui Wenโ€™s research. In partnership with Professor Xiangqin Liu at Dalhousie University, he made a breakthrough in spider silk research, co-authoring a paper that introduced the first full-length coding gene for wrapped silk protein in China. This finding, published in International Journal of Biological Macromolecules in 2018, represents a critical contribution to the genetic understanding of spider silk and has furthered his professional reputation. He also maintains professional connections with colleagues Xue Li, Kangkang Wang, Suyang Wang, and Qing Meng, contributing to a network that fosters innovation in biomaterials.

Editorial Appointments and Review Responsibilities ๐Ÿ“

Rui Wenโ€™s editorial and review roles reflect his expertise in biomaterials. He serves on the editorial board of the World Journal of Biological Chemistry and the Young Editorial Board for Biomedical Engineering Communications. Additionally, he acts as an invited reviewer for the International Journal of Biological Macromolecules. These positions allow him to shape the discourse in biomaterials and bioengineering while staying updated on the latest scientific advancements.

Professional Associations and Memberships ๐Ÿ›๏ธ

Rui Wen is actively engaged with the scientific community through his memberships in professional associations alongside prominent researchers such as Xue Li and Kangkang Wang. These affiliations support his commitment to collaborative research and knowledge sharing within the biomaterials field.

Training, Workshops, and Oral Presentations ๐ŸŽค

Throughout his career, Rui Wen has participated in workshops and conferences focused on materials science, biomimetics, and spider silk research. His presentations have contributed to the broader understanding of silk protein synthesis and fiber properties. These opportunities have enabled him to refine his expertise, exchange ideas with other experts, and enhance the visibility of his work.

Key Contributions to Biomimetic Research ๐ŸŒ

Rui Wenโ€™s contributions to biomimetic research are centered on unraveling the complexities of spider silk proteins. By systematically studying the molecular composition of spider wrapping silk fibers, he has identified key proteins that contribute to the materialโ€™s exceptional properties. His insights into the protein composition and molecular weight relationships have been instrumental in developing high-performance synthetic fibers that may one day be applied in various fields, from medicine to aerospace.

Success Factors and Research Milestones ๐Ÿ†

Rui Wen attributes his success to a disciplined approach to research, continuous learning, and collaborative engagement. His landmark achievements, including the genetic analysis of spider silk proteins and the development of artificial silk fibers with improved extensibility, mark important milestones in the field of biomaterials. His work has garnered attention for its potential to revolutionize sustainable material synthesis.

Publications and Laboratory Experience ๐Ÿงช

With over 16 publications in SCI-indexed and Scopus journals, Rui Wenโ€™s scholarly output reflects a high level of scientific rigor. His laboratory experience encompasses advanced techniques in protein characterization, gene sequencing, and fiber synthesis. In the lab, he works with state-of-the-art equipment to explore the biomimetic applications of silk proteins and innovate synthetic fiber production.

Sustainable Silk-Based Materials ๐ŸŒฑ

Looking ahead, Rui Wen envisions a future where artificial spider silk fibers play a role in sustainable development. His ongoing research on silk protein functions and fiber synthesis holds promise for reducing the environmental impact of synthetic materials. Through continuous innovation, he aims to create sustainable materials that meet the demands of modern industries while preserving natural resources.

๐Ÿ“–Publications:

Paper Title: Physical Properties of the Second Type of Aciniform Spidroin (AcSp2) from Neoscona theisi Reveal a pH-Dependent Self-Assembly Repetitive Domain

  • Authors: Yang, D., Wang, S., Wang, K., Zan, X., Wen, R.
  • Journal: ACS Biomaterials Science and Engineering
  • Year: 2023

Paper Title: Complete gene sequence and mechanical property of the fourth type of major ampullate silk protein

  • Authors: Wen, R., Wang, S., Wang, K., Zan, X., Meng, Q.
  • Journal: Acta Biomaterialia
  • Year: 2023

Paper Title: Characterization of two full-length tubuliform silk gene sequences from Neoscona theisi reveals intragenic concerted evolution and multiple copies in genome

  • Authors: Wen, R., Wang, K., Zan, X.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2022

Paper Title: Characterization of two full-length Araneus ventricosus major ampullate silk protein genes

  • Authors: Wen, R., Yang, D., Wang, K., Zan, X.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2022

Paper Title: The novel aciniform silk protein (AcSp2-v2) reveals the unique repetitive domain with high acid and thermal stability and self-assembly capability

  • Authors:Wen, R., Wang, K., Yang, D., Zan, X., Meng, Q.
  • Journal: International Journal of Biological Macromolecules
  • Year: 2022